
Marksman · physical (AD) damage
Later items show higher win rates partly because games that last that long are usually already being won. Compare items within a slot, not across slots.
Sorcery
Summon Aery
Arcane Comet
Deathfire Touch
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
Inspiration
Glacial Augment
Unsealed Spellbook
First Strike
Hextech Flashtraption
Magical Footwear
Cash Back
Triple Tonic
Time Warp Tonic
Biscuit Delivery
Cosmic Insight
Approach Velocity
Jack Of All Trades

Based on 12,319 games · 50.7% win rate · High elo · patch 26.20.
Later items show higher win rates partly because games that last that long are usually already being won. Compare items within a slot, not across slots.
Sorcery
Summon Aery
Arcane Comet
Deathfire Touch
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
Inspiration
Glacial Augment
Unsealed Spellbook
First Strike
Hextech Flashtraption
Magical Footwear
Cash Back
Triple Tonic
Time Warp Tonic
Biscuit Delivery
Cosmic Insight
Approach Velocity
Jack Of All Trades

Based on 6,314 games · 52.3% win rate · High elo · patch 26.20.
Later items show higher win rates partly because games that last that long are usually already being won. Compare items within a slot, not across slots.
Precision
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Resolve
Grasp of the Undying
Aftershock
Guardian
Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching

Based on 116 games · 60.3% win rate · High elo · patch 26.20.

When units die near Senna, their souls are periodically trapped by the Black Mist. Senna can attack these souls to free them, absorbing the Mist that held them in death. Mist fuels her Relic Cannon's power with increased Attack Damage, Attack Range, and Critical Strike Chance. Attacks from Senna's Relic Cannon take longer to fire, deal bonus damage, and briefly grant her a portion of her target's Move Speed.

From the twin barrels of her Relic Cannon, Senna fires a unified beam of light and shadow through a target, healing allies and damaging enemies.

Senna sends forth a wave of Black Mist. If it hits an enemy it latches onto them hungrily, rooting them and everything nearby after a brief delay.

Senna draws the Mist she has stored in her weapon into a storm around her, embracing darkness and becoming a wraith within. Allies who enter the area are camouflaged and also appear as wraiths as the Mist shrouds them. Wraiths gain increased Move Speed, are unselectable, and hide their identities.

Senna calls upon the relic stones of fallen Sentinels, splitting her relic cannon into a holy array of shadow and light. She then fires a global beam that shields allies from harm, while damaging enemies caught in the center.
W Last EmbraceSlowignores tenacityFROM
Q Piercing DarknessTheir hard CC is tenacity-reducible, so Mercury's Treads and tenacity items shorten their lockdown.
Tap or hover a crowd-control type to see which ability it comes from.